Does Mounjaro Cause Hair Loss? Here’s What Studies Actually Show

In the ever-evolving world of health and wellness, new topics frequently capture the public’s attention.

One such topic that has recently been trending is the potential link between Mounjaro and hair loss.

This article aims to delve into this subject, providing readers with a comprehensive understanding based on the latest research and expert opinions.

The interest in Mounjaro and its effects on the body, particularly hair loss, has seen a significant surge in recent times.

This is evident from the increasing number of online searches and discussions on various health and wellness forums.

However, with the abundance of information available, it can be challenging to separate fact from fiction. That’s where this article comes in.

What is Mounjaro?

Mounjaro is a brand-name prescription medication that contains the active drug tirzepatide.

It’s an injectable medicine that comes in the form of a subcutaneous injection, which is administered under the skin.

Primary Uses of Mounjaro

Mounjaro is primarily used to manage blood sugar levels in adults with type 2 diabetes.

It’s used in conjunction with diet and exercise to improve blood glucose control. Please note that Mounjaro is not for use in people with type 1 diabetes.

How Mounjaro Works in the Body

Mounjaro is the first dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist.

It works on the GIP receptors and the GLP-1 receptors, which are natural incretin hormones that help regulate blood sugar levels.

Mounjaro helps to lower blood sugar by:

  • Increasing insulin production in the pancreas.
  • Reducing sugar production in the liver.
  • Slowing the rate food passes through your body, making you feel full longer.

It’s important to note that while Mounjaro’s active ingredient, tirzepatide, is approved for weight loss under the brand name Zepbound, Mounjaro itself is not approved for weight loss by the FDA.

Common Side Effects of Mounjaro

Mounjaro, like any medication, can cause side effects. The most commonly reported side effects of Mounjaro include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Decreased appetite
  • Constipation
  • Abdominal pain

These side effects are typically mild and tend to occur at the beginning of treatment or when the dose is increased.

Managing Side Effects

Most people find that these side effects lessen or even disappear after a few weeks of treatment.

Here are some tips for managing these side effects:

  • Eat more slowly and consume smaller meals to help manage nausea and other stomach-related side effects.
  • Select more bland, low-fat foods (like crackers, toast, and rice) if you’re experiencing nausea or other stomach discomfort.
  • Stay hydrated, especially if you’re experiencing diarrhea.

Mounjaro and Hair Loss: What Does the Research Say?

The relationship between Mounjaro and hair loss is a topic of interest, especially given the recent surge in discussions and online searches.

However, it’s important to note that there is currently no definitive proof that Mounjaro directly causes hair loss.

Understanding the Connection

While hair loss is not listed as a common side effect of Mounjaro, some people have reported experiencing hair loss while using the drug.

Experts believe that this is often due to a condition known as telogen effluvium, where a stressor (like rapid weight loss) triggers hair loss.

Insights from Clinical Trials and Studies

A meta-analysis performed on 8 studies, with a total number of 8847 participants who received Mounjaro over 2 years, revealed that approximately 5.7% of them experienced alopecia.

A different study found a 4% hair loss rate in patients treated with tirzepatide (the active substance in Mounjaro), compared to 0.7% in the placebo group.

In a clinical trial for tirzepatide’s effects on weight loss, nearly 6% of people taking the highest dose reported alopecia — a generic word for any type of hair loss — compared to 1% of those who got a placebo.

Tirzepatide drugmaker Eli Lilly said in a statement that the hair loss seen in the clinical trial was generally short-lived.

Understanding Hair Loss

Hair loss, also known as alopecia, can occur due to a variety of reasons.

Here are some of the common causes:

  • Hereditary Factors: The most common cause of hair loss is a hereditary condition known as androgenetic alopecia, which can affect both men and women.
  • Hormonal Changes: Hormonal imbalances caused by pregnancy, menopause, or certain medical conditions can lead to temporary or permanent hair loss.
  • Medical Conditions: Certain medical conditions such as scalp infections, lupus, and an autoimmune disorder known as alopecia areata can cause hair loss.
  • Medications and Supplements: Certain drugs, including those used for cancer, arthritis, depression, heart problems, gout, and high blood pressure, can cause hair loss.
  • Radiation Therapy: Radiation therapy to the head can result in hair loss.
  • Certain Hairstyles and Treatments: Hairstyles that pull your hair tight, such as pigtails or cornrows, can cause a type of hair loss called traction alopecia. Hot oil hair treatments and permanents can cause inflammation of hair follicles that leads to hair loss.

Weight Loss and Hair Shedding

Significant weight loss, especially if it’s rapid and involves extreme calorie restriction, can lead to hair loss.

This problem is known as telogen effluvium, where hair follicles take a break earlier than they should because of stress on the body.

Rapid weight loss can shock the body, pushing hair follicles into the resting phase too soon, which increases hair shedding.

This is often temporary, and your hair will usually start to regrow as your body adjusts to the weight loss, as long as you’re also getting the right nutrients by eating a healthy, balanced diet.

It’s important to note that if you’re losing hair and losing weight, it may be due to another underlying medical condition, such as having an overactive or underactive thyroid.

Managing Side Effects and Concerns

Mounjaro, like any medication, can cause side effects. However, these side effects are usually manageable and often lessen or disappear over time.

Here are some tips to help manage potential side effects:

  1. Eat More Slowly and Consume Smaller Meals: This can help manage stomach-related side effects like nausea.
  2. Select More Bland, Low-Fat Foods: Foods like crackers, toast, and rice can help if you’re experiencing nausea or other stomach discomfort.
  3. Stay Hydrated: Especially if you’re experiencing diarrhea.
  4. Get Fresh Air Regularly: This can help manage nausea.
  5. Cut Down on Sugar and High-Fat Foods: This can help manage stomach-related side effects.
  6. Avoid Strong-Smelling Meals: This can help manage nausea.
  7. Drink Chamomile Tea or Ginger Ale: These can help ease nausea.
  8. Take Over-The-Counter Meds: These can help manage nausea.

When to Seek Medical Advice

While most side effects of Mounjaro are manageable, it’s important to know when to seek medical advice.

Contact your healthcare provider if you experience any of the following:

  • Severe Stomach Pain: If it persists for more than 6 hours.
  • Intense Nausea: Resulting in repeated vomiting and preventing hydration.
  • Symptoms of Thyroid Cancer: Such as difficulty swallowing, shortness of breath, hoarseness, or an unusual neck lump.
  • Abdominal Pain, Dizziness, Severe Stomach Problems, or Severe Dehydration: You should seek medical advice immediately and inform them that you’re using Mounjaro.
  • Symptoms of an Allergic Reaction: Such as difficulty breathing, a skin rash, or swelling of the lips, face, or tongue.


Mounjaro’s link to hair loss is unclear. Research suggests a possible connection, but it might be due to rapid weight loss, a common Mounjaro effect. Hair loss has various causes.

If you experience hair loss with Mounjaro, consult your doctor to explore underlying causes and manage potential side effects.

Remember, communication with your healthcare provider is key for a safe and successful Mounjaro experience.


Hi there, I'm Pranay, a fitness enthusiast who loves working out regularly and staying in shape. I'm passionate about health and fitness, and I'm always on the lookout for new and exciting ways to stay active and healthy.

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